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Dantrium Generic Dantrolene

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IndicationsDANTRIUM is indicated in controlling the manifestations of clinical spasticity resulting from serious chronic disorders such as spinal cord injury stroke cerebral palsy or multiple sclerosis. It is of particular benefit to the patient whose functional rehabilitation has been retarded by the sequelae of spasticity. Such patients must have presumably reversible spasticity where relief of spasticity will aid in restoring residual function. There is no evidence that patients with contractures will benefit. DANTRIUM is not indicated in the treatment of skeletal muscle spasm resulting from rheumatic disorders or electroconvulsive therapy.If improvement occurs it will ordinarily occur within the dosage titration schedule (see DOSAGE AND ADMINISTRATION) as manifested by a decrease in the severity of spasticity and the ability to resume a daily function not quite attainable without DANTRIUM.Occasionally subtle but meaningful improvements in spasticity may occur with DANTRIUM therapy. In such instances information regarding improvement should be solicited from the patient and those who are in constant daily contact and attendance with him. Brief withdrawal of DANTRIUM for a period of 2 to 4 days will frequently demonstrate exacerbation of the manifestation of spasticity and may serve to confirm a clinical impression.A decision to continue the administration of DANTRIUM on a long term basis is justified if introduction of the drug into the patient's regimen produces a significant reduction in painful and/or disabling spasticity such as clonus or permits a significant reduction in the intensity and/or degree of nursing care required or rids the patient of an annoying manifestation of spasticity considered important by the patient himself.Dosage and Administration:Prior to the administration of DANTRIUM consideration should be given to the potential response to treatment. A decrease in spasticity sufficient to allow a daily function not otherwise attainable should be the therapeutic goal of treatment with DANTRIUM. Refer to the INDICATIONS section for a description of the response to be anticipated.It is important to establish a therapeutic goal (regain and maintain a specific function such as therapeutic exercise program utilisation of braces transfer manoeuvres etc.) before beginning DANTRIUM therapy. Dosage should be increased until the maximum performance compatible with the dysfunction due to underlying disease is achieved. No further increase in dosage is then indicated.Usual Dosage It is important that the dosage be titrated and individualised for maximum effect. The lowest dose compatible with optimal response is recommended.In view of the potential for liver damage in long-term DANTRIUM use therapy should be stopped if benefits are not evident within 45 days.Adults Begin therapy with 25 mg once daily; increase to 25 mg two three or four times daily and then by increments of 25 mg up to as high as 50 mg two three or four times daily if necessary. The maximum recommended dose is 200 mg/day. As most patients will respond to this or a lower dose and hepatotoxicity appears to be dose-related above 200 mg/day higher doses should be used only rarely and with close monitoring. (See WARNINGS). Doses higher than 400 mg/day should not be used.Each dosage level should be maintained for four to seven days to determine the patient's response. The dose should not be increased beyond and may even have to be reduced to the amount at which the patient received maximal benefit without adverse effects.Children A similar approach should be utilised starting with 0.5 mg/kg of body weight twice daily; this is increased to 0.5 mg/kg three or four times daily and then by increments to a maximum of 2 mg/kg three times a day. Doses higher than 50 mg four times daily should not be used in children.

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Women's Health: Aygestin (Norethindrone Acetate) Aygestin (Norethindrone Acetate) is a progestin used to treat endometriosis a disorder of the lining of the uterus. It may also be used to treat menstrual disorders and to treat other conditions as determined by your doctor. Buy Aygestin (Norethindrone Acetate) and other Women's Health products online at Medstore. About Aygestin (Norethindrone Acetate): Product Type: Women's Health Brand name: Aygestin Generic name: Norethindrone Acetate What is the most important information I should know about Aygestin? • Using Aygestin while you are pregnant can cause harm to the unborn baby. Do not use Aygestin if you are pregnant. Stop using the medication and tell your doctor if you become pregnant during treatment. • Avoid smoking cigarettes while taking Aygestin. Smoking increases your risk of developing a heart attack stroke or blood clot. • Aygestin does not protect you from sexually transmitted diseases — including HIV and AIDS. Using a condom is the only way to help protect yourself from these diseases. What is Aygestin? • Aygestin is a form of progesterone a female hormone. • Aygestin is used for birth control (contraception) to prevent pregnancy. Aygestin is also used to treat menstrual disorders endometriosis or abnormal vaginal bleeding caused by a hormone imbalance. • Aygestin may also be used for purposes other than those listed in this medication guide. What should I discuss with my healthcare provider before using Aygestin? • Aygestin is in the FDA pregnancy category X. This means that using the medication while you are pregnant can cause birth defects in the baby. Do not take Aygestin if you are pregnant. Stop taking the medication and tell your doctor if you become pregnant. If you plan to become pregnant after you stop taking Aygestin ask your doctor how long you should wait before trying to get pregnant. • You should not take Aygestin if you have: a history of stroke or blood clots; liver disease; a history of stroke or blood clots; cancer of the breast of ovary; unusual vaginal bleeding that a doctor has not diagnosed; or complications from a recent miscarriage or abortion. • Taking Aygestin may be dangerous if you have any of the conditions listed above. • Before taking Aygestin tell your doctor if you have: high blood pressure angina or heart disease; a bleeding disorder such as hemophilia; diabetes; high cholesterol; migraines; a history of depression or mental illness; asthma; or seizures or epilepsy. • If you have any of the conditions listed above you may not be able to use Aygestin or you may require a dosage adjustment or special monitoring during treatment. • This medication can pass into breast milk and may harm a nursing baby. Do not use Aygestin without telling your doctor if you are breast-feeding. • Taking Aygestin can cause you to have unusual results to certain medical tests. Tell any doctor who treats you that you are using Aygestin. How should I take Aygestin? • The dose schedule for Aygestin may be different for birth control than for treating other conditions. To best treat your condition Aygestin should be used exactly as your doctor has prescribed it for you. Do not use more of the medication than recommended. Do not take Aygestin for longer than your doctor has prescribed. • Take the medication at the same time each dose day. Taking a pill late or missing a pill can increase your chances of having breakthrough bleeding or getting pregnant. • For birth control start a new pack of pills the day after your last pack is finished. There is no break between packs. • If you vomit soon after taking Aygestin use a backup method of birth control (such as a condom and/ or spermicide) for 48 hours. • You may have some light bleeding or spotting between periods. Continue taking Aygestin even if this occurs. • If your menstrual period is late you may be pregnant. If it has been more than 45 says since the start of your last period call your doctor or use a home pregnancy test. • You will need to have yearly physical exams and Pap smears while you are using Aygestin. Examine your breasts at home every month to check for lumps. It is important that you not miss any scheduled visits to your doctor. • After you stop using Aygestin you may start bleeding within a few days. • Store Aygestin at room temperature away from moisture and heat. What happens if I miss a dose? • Take the missed dose as soon as you remember. Then take the next dose at your regularly scheduled time. Do not take extra medicine to make up the missed dose. • If you were more than 3 hours late in taking your dose use a backup method of birth control (such as a condom and/ or spermicide). Keep using the backup method for at least 48 hours to ensure protection from pregnancy. • If you are not sure what to do about a missed dose keep taking Aygestin and use a backup method of birth control until you can talk to your doctor. What happens if I overdose? • An overdose of Aygestin is not likely to cause serious overdose symptoms. Call your doctor if you think you have used too much of this medicine. • Symptoms of a Aygestin overdose have not been reported. What should I avoid while taking Aygestin? • Women who use hormone medication should not smoke. Smoking will increase your risk of having a serious side effect from Aygestin such as heart attack stroke or a blood clot. • Aygestin does not protect you from sexually transmitted diseases — including HIV and AIDS. Using a condom is the only way to protect yourself from these diseases. What are the possible side effects of Aygestin? • Stop using Aygestin and call your doctor at once if you have any of these serious side effects: an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips tongue or face; or hives); abnormal vaginal bleeding; late or missed menstrual period; a partial or complete loss of vision blurred vision double vision or a sudden onset of bulging eyes; sudden and severe headache pain behind your eyes dizziness or fainting; speech problems; vomiting or jaundice (yellowing of the skin or eyes); or sudden or severe pain in your lower stomach. • Other less serious side effects may be more likely to occur. Continue to take Aygestin and talk to your doctor if you experience: nausea; swollen or tender breasts; sleep problems (insomnia); depression mood swings; acne freckles or darkened skin areas; increased hair growth; weight gain or loss; or changes in your menstrual cycle or vaginal discharge. • Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. What other drugs will affect Aygestin? • Before taking Aygestin tell your doctor if you are taking any of the following medicines: rifampin (Rifadin); phenytoin (Dilantin); carbamazepine (Tegretol); or a barbiturate such as amobarbital (Amytal) butabarbital (Butisol) mephobarbital (Mebaral) secobarbital (Seconal) or phenobarbital (Luminal Solfoton). • If you are using any of these drugs Aygestin may not work as well and you may get pregnant. You may need to use a second form of birth control if you are taking any of the medicines listed above. • There may be other drugs not listed that can affect Aygestin. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins minerals herbal products and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. 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